The composite CVD or death outcome was rare 0. Greater weight loss without increased risk of incident CVD or death was observed in patients using phentermine monotherapy for longer than 3 months.
Despite the limitations of the observational design, this study supports the effectiveness and safety of longer-term phentermine use for low-risk individuals. Cell Metab. We have detected that you are using an Ad Blocker. PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker. We have sent a message to the email address you have provided,. If this email is not correct, please update your settings with your correct address.
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This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Phentermine oral capsule can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Taking certain drugs with phentermine may cause serious side effects. Examples of these drugs include:. Taking phentermine with certain medications may cause more side effects.
However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Taking it again could be fatal cause death. The use of drinks that contain alcohol can increase your risk of side effects from phentermine.
These side effects can include dizziness, feeling nervous and excitable, headache, hard stools or diarrhea, dry mouth, and not being able to sleep. They can also include decreased interest in sex or change in ability to have sex.
If you drink alcohol, talk to your doctor. You may need to be more closely monitored for side effects. Phentermine may make your PPH worse. These include stroke, arrhythmia irregular heartbeat , heart failure, coronary artery disease, valve disease, and uncontrolled high blood pressure. Phentermine may cause a serious increase in your blood pressure.
This may make your heart work harder. The extra stress on your heart may make your heart disease worse. For people with history of hyperthyroidism: Tell your doctor if you have hyperthyroidism an overactive thyroid. Phentermine may increase your thyroid activity. This may raise your thyroid levels even further.
For people with glaucoma: This drug may increase your eye pressure even more. This may cause permanent damage to your vision. Tell your doctor if you have glaucoma. Your doctor may lower the dosage of your diabetes drugs.
For people with a history of drug misuse: This drug may be habit-forming. Tell your doctor if you have a history of drug or alcohol misuse. For people with agitation: This drug may cause restlessness and anxiety and may make your agitation worse.
For pregnant women: Phentermine is a category X pregnancy drug. That means two things:. Stop taking phentermine and call your doctor right away if you become pregnant while taking this drug.
For women who are breastfeeding: Phentermine may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication. For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time.
This raises your risk of side effects. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:.
Phentermine is stored in body fat and burning fat may support elimination. That said, there is no healthy way to speed up this process. If you are expecting to be tested for Adipex, disclose that you are taking it or stop using it prior to being tested. People prescribed Adipex for weight loss often expect to take it for several weeks. Plan ahead. Keep in mind that if you are using the drug as prescribed by your doctor, it is not a problem for Adipex to show up on a drug test.
Phentermine has stimulant properties and can impact neurotransmitters including dopamine, norepinephrine, and serotonin. This is very similar to amphetamines. For this reason, prescriptions are tightly regulated and often only allowed for short periods of time.
It is not recommended for people with a history of stimulant use disorder. Some of the serious side effects of Adipex include increased blood pressure, heart palpitations, restlessness, dizziness, tremor, insomnia, shortness of breath, chest pain, and swelling of the legs and ankles.
Adipex overdose symptoms, on the other hand, may include:. If you think someone has overdosed on any phentermine medication, call the poison control center at If the victim has collapsed or is not breathing, call immediately. It is important that you discuss all of your medications and supplements with your doctor to avoid drug interactions. Drugs of special concern include those used to treat depression and similar conditions, including:.
Your doctor should also be made aware of any previous heart conditions, including high blood pressure and arteriosclerosis, or if you have hyperthyroidism.
It's also best to avoid using alcohol while taking Adipex as the combination can intensify the effects. Withdrawal symptoms from Adipex use tend to peak within the first couple of days and diminish over the next week. Common withdrawal symptoms from Adipex include:. If you are taking Adipex regularly at a high dose and stop taking it too soon, you can be at risk for more serious problems, including:. Adipex and other phentermine-containing medications may be available by prescription and can help with your weight loss goals.
However, it is important to realize that there are potential risks involved, including developing a dependence and even a stimulant use disorder. It could become difficult for you to concentrate without taking Adipex. You could enter into unhealthy cycles of taking more and less of the drug that put dangerous strain on your cardiovascular system.
Cravings for Adipex that end up interfering with your everyday life are cause for speaking with a mental health professional. Counseling or group therapy can help you understand the reasons for your Adipex use and develop alternatives and strategies to slowly stop using. Harm reduction psychotherapy and abstinence-based programs are both available depending on what you feel is best for you.
If you or a loved one is experiencing symptoms of Adipex addiction, help is available. Learn the best ways to manage stress and negativity in your life. One hundred false-positive amphetamine specimens characterized by liquid chromatography time-of-flight mass spectrometry. J Anal Toxicol. National Library of Medicine.
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